Addison Disease

An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.

Also Known As:

Addison's Disease; Addisons Disease; Primary Adrenal Insufficiency; Primary Adrenocortical Insufficiency; Primary Hypoadrenalism; Adrenal Insufficiency, Primary; Adrenocortical Insufficiencies, Primary; Adrenocortical Insufficiency, Primary; Disease, Addison; Hypoadrenalism, Primary; Hypoadrenalisms, Primary; Insufficiencies, Primary Adrenocortical; Insufficiency, Primary Adrenocortical; Primary Adrenocortical Insufficiencies

Endocrine System Diseases: 968
- Adrenal Gland Diseases: 24
  - Adrenal Insufficiency: 3937
    - Addison Disease: 1725
Immune System Diseases: 4321
- Autoimmune Diseases: 34618
  - Addison Disease: 1725

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Disease

Drug/Important Bio-Agent (IBA)